Odds are good that there's a mass extinction going on right now. It will be only one of six in the entire history of the planet. In the past these great die-offs have been caused by asteroid impacts and rapid, devastating climate change driven by volcanism.
This time it's driven by you and me.
How does that make you feel? How should that make you feel? The answer to this question depends mightily on what you think of as nature and where you think we fit into it.